Antibiotic prescription practices in primary care in low- and middle-income countries: A systematic review and meta-analysis

Antibiotic prescription practices in primary care in low- and middle-income countries: A systematic review and meta-analysis

By Giorgia Sulis, Pierrick Adam, Vaidehi Nafade, Genevieve Gore, Benjamin Daniels, Amrita Daftary, Jishnu Das, Sumanth Gandra, and Madhukar Pai
Plos Medicine, 16 June 2020

The widespread use of antibiotics plays a major role in the development and spread of antimicrobial resistance. However, important knowledge gaps still exist regarding the extent of their use in low- and middle-income countries (LMICs), particularly at the primary care level. We performed a systematic review and meta-analysis of studies conducted in primary care in LMICs to estimate the prevalence of antibiotic prescriptions as well as the proportion of such prescriptions that are inappropriate.